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Efficient and Selective Prevention of GVHD by Antigen-Specific Induced Tregs via Linked-Suppression in Mice

Naturally occurring regulatory T cells (nTregs) suppress the development of GVHD and may spare graft-versus-leukemia (GVL) effect. Because nTreg is a rare population in a healthy individual, the limited source and the non-selective suppression are major hurdles towards the application of nTregs in t...

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Detalhes bibliográficos
Main Authors: Semple, Kenrick, Yu, Yu, Wang, Dapeng, Anasetti, Claudio, Yu, Xue-Zhong
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039088/
https://ncbi.nlm.nih.gov/pubmed/21224010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2010.12.710
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