CD8(+) Tregs promote GVHD prevention and overcome the impaired GVL effect mediated by CD4(+) Tregs in mice

Adoptive natural regulatory T cell (nTreg) therapy has improved the outcome for patients suffering from graft-versus-host disease (GVHD) following allogeneic hematopoietic cell transplantation (Allo-HCT). However, fear of broad immune suppression and subsequent dampening of beneficial graft-versus-l...

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Dades bibliogràfiques
Publicat a:Oncoimmunology
Autors principals: Heinrichs, Jessica, Li, Jun, Nguyen, Hung, Wu, Yongxia, Bastian, David, Daethanasanmak, Anusara, Sofi, M-Hanief, Schutt, Steven, Liu, Chen, Jin, Junfei, Betts, Brian, Anasetti, Claudio, Yu, Xue-Zhong
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2016
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938369/
https://ncbi.nlm.nih.gov/pubmed/27471614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1146842
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