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The G(1 )phase Cdks regulate the centrosome cycle and mediate oncogene-dependent centrosome amplification

Because centrosome amplification generates aneuploidy and since centrosome amplification is ubiquitous in human tumors, a strong case is made for centrosome amplification being a major force in tumor biogenesis. Various evidence showing that oncogenes and altered tumor suppressors lead to centrosome...

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Detaylı Bibliyografya
Asıl Yazarlar: Harrison, Mary K, Adon, Arsene M, Saavedra, Harold I
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038874/
https://ncbi.nlm.nih.gov/pubmed/21272329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1747-1028-6-2
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