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The G(1 )phase Cdks regulate the centrosome cycle and mediate oncogene-dependent centrosome amplification
Because centrosome amplification generates aneuploidy and since centrosome amplification is ubiquitous in human tumors, a strong case is made for centrosome amplification being a major force in tumor biogenesis. Various evidence showing that oncogenes and altered tumor suppressors lead to centrosome...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3038874/ https://ncbi.nlm.nih.gov/pubmed/21272329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1747-1028-6-2 |
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