Načítá se...
Cdk2 and Cdk4 Regulate the Centrosome Cycle and Are Critical Mediators of Centrosome Amplification in p53-Null Cells
The two mitotic centrosomes direct spindle bipolarity to maintain euploidy. Centrosome amplification—the acquisition of ≥3 centrosomes—generates multipolar mitoses, aneuploidy, and chromosome instability to promote cancer biogenesis. While much evidence suggests that Cdk2 is the major conductor of t...
Uloženo v:
| Hlavní autoři: | , , , , , , |
|---|---|
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology (ASM)
2010
|
| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2812235/ https://ncbi.nlm.nih.gov/pubmed/19933848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00253-09 |
| Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!
|