Regulatory T cells facilitate the nuclear accumulation of inducible cAMP early repressor (ICER) and suppress nuclear factor of activated T cell c1 (NFATc1)

Inducible cAMP early repressor (ICER) is a transcriptional repressor, which, because of alternate promoter use, is generated from the 3′ region of the cAMP response modulator (Crem) gene. Its expression and nuclear occurrence are elevated by high cAMP levels in naturally occurring regulatory T cells...

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Bibliographische Detailangaben
Hauptverfasser: Vaeth, Martin, Gogishvili, Tea, Bopp, Tobias, Klein, Matthias, Berberich-Siebelt, Friederike, Gattenloehner, Stefan, Avots, Andris, Sparwasser, Tim, Grebe, Nadine, Schmitt, Edgar, Hünig, Thomas, Serfling, Edgar, Bodor, Josef
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2011
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038697/
https://ncbi.nlm.nih.gov/pubmed/21262800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1009463108
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