Regulatory T cells facilitate the nuclear accumulation of inducible cAMP early repressor (ICER) and suppress nuclear factor of activated T cell c1 (NFATc1)

Inducible cAMP early repressor (ICER) is a transcriptional repressor, which, because of alternate promoter use, is generated from the 3′ region of the cAMP response modulator (Crem) gene. Its expression and nuclear occurrence are elevated by high cAMP levels in naturally occurring regulatory T cells...

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Detalhes bibliográficos
Main Authors: Vaeth, Martin, Gogishvili, Tea, Bopp, Tobias, Klein, Matthias, Berberich-Siebelt, Friederike, Gattenloehner, Stefan, Avots, Andris, Sparwasser, Tim, Grebe, Nadine, Schmitt, Edgar, Hünig, Thomas, Serfling, Edgar, Bodor, Josef
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038697/
https://ncbi.nlm.nih.gov/pubmed/21262800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1009463108
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