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Homing endonucleases: from microbial genetic invaders to reagents for targeted DNA modification
Homing endonucleases are microbial DNA-cleaving enzymes that mobilize their own reading frames by generating double strand breaks at specific genomic invasion sites. These proteins display an economy of size, and yet recognize long DNA sequences (typically 20 to 30 basepairs). They exhibit a wide ra...
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| Autor principal: | |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3038549/ https://ncbi.nlm.nih.gov/pubmed/21220111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2010.12.003 |
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