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Mitochondria as Crucial Players in Demyelinated Axons: Lessons from Neuropathology and Experimental Demyelination

Mitochondria are the most efficient producers of energy in the form of ATP. Energy demands of axons, placed at relatively great distances from the neuronal cell body, are met by mitochondria, which when functionally compromised, produce reactive oxygen species (ROS) in excess. Axons are made metabol...

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Autors principals: Campbell, Graham R., Mahad, Don J.
Format: Artigo
Idioma:Inglês
Publicat: SAGE-Hindawi Access to Research 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038418/
https://ncbi.nlm.nih.gov/pubmed/21331147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/262847
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