Mitochondrial immobilization mediated by syntaphilin facilitates survival of demyelinated axons

Axonal degeneration is a primary cause of permanent neurological disability in individuals with the CNS demyelinating disease multiple sclerosis. Dysfunction of axonal mitochondria and imbalanced energy demand and supply are implicated in degeneration of chronically demyelinated axons. The purpose o...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ohno, Nobuhiko, Chiang, Hao, Mahad, Don J., Kidd, Grahame J., Liu, LiPing, Ransohoff, Richard M., Sheng, Zu-Hang, Komuro, Hitoshi, Trapp, Bruce D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2014
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4103317/
https://ncbi.nlm.nih.gov/pubmed/24958879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1401155111
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