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Myelination and Axonal Electrical Activity Modulate the Distribution and Motility of Mitochondria at CNS Nodes of Ranvier

Energy production presents a formidable challenge to axons as their mitochondria are synthesized and degraded in neuronal cell bodies. To meet the energy demands of nerve conduction, small mitochondria are transported to and enriched at mitochondrial stationary sites located throughout the axon. In...

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Hlavní autoři: Ohno, Nobuhiko, Kidd, Grahame J., Mahad, Don, Kiryu-Seo, Sumiko, Avishai, Amir, Komuro, Hitoshi, Trapp, Bruce D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139464/
https://ncbi.nlm.nih.gov/pubmed/21593309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0095-11.2011
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