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Myelin Galactolipids Are Essential for Proper Node of Ranvier Formation in the CNS

The vertebrate myelin sheath is greatly enriched in the galactolipids galactocerebroside (GalC) and sulfatide. Mice with a disruption in the gene that encodes the biosynthetic enzyme UDP-galactose:ceramide galactosyl transferase (CGT) are incapable of synthesizing these lipids yet form myelin sheath...

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Detalles Bibliográficos
Publicado en:J Neurosci
Autores principales: Dupree, Jeffrey L., Coetzee, Timothy, Blight, Andrew, Suzuki, Kinuko, Popko, Brian
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 1998
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6792626/
https://ncbi.nlm.nih.gov/pubmed/9464989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-05-01642.1998
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