Effects of chronic ethanol feeding on rat hepatocytic glutathione. Relationship of cytosolic glutathione to efflux and mitochondrial sequestration.

Chronic ethanol feeding to rats increases the sinusoidal component of hepatic glutathione (GSH) efflux, despite a lower steady-state GSH pool size. In the present studies, no increase of biliary GSH efflux in vivo was found in chronic ethanol-fed cells. Studies were performed on ethanol-fed and pair...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Fernandez-Checa, J C, Ookhtens, M, Kaplowitz, N
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1989
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303814/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2703532/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114008
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