Effects of chronic ethanol feeding on rat hepatocytic glutathione. Relationship of cytosolic glutathione to efflux and mitochondrial sequestration.

Chronic ethanol feeding to rats increases the sinusoidal component of hepatic glutathione (GSH) efflux, despite a lower steady-state GSH pool size. In the present studies, no increase of biliary GSH efflux in vivo was found in chronic ethanol-fed cells. Studies were performed on ethanol-fed and pair...

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Publié dans:	J Clin Invest
Auteurs principaux:	Fernandez-Checa, J C, Ookhtens, M, Kaplowitz, N
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Clinical Investigation 1989
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303814/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2703532/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114008
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