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Effects of chronic ethanol feeding on rat hepatocytic glutathione. Relationship of cytosolic glutathione to efflux and mitochondrial sequestration.

Chronic ethanol feeding to rats increases the sinusoidal component of hepatic glutathione (GSH) efflux, despite a lower steady-state GSH pool size. In the present studies, no increase of biliary GSH efflux in vivo was found in chronic ethanol-fed cells. Studies were performed on ethanol-fed and pair...

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Dades bibliogràfiques
Publicat a:J Clin Invest
Autors principals: Fernandez-Checa, J C, Ookhtens, M, Kaplowitz, N
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 1989
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303814/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2703532/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114008
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