Inhibition of poly(ADP-ribose) polymerase activity is insufficient to induce tetraploidy

Poly(ADP-ribose) polymerase (PARP) knockout mice are resistant to murine models of human diseases such as cerebral and myocardial ischemia, traumatic brain injury, diabetes, Parkinsonism, endotoxic shock and arthritis, implicating PARP in the pathogenesis of these diseases. Potent selective PARP inh...

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Autors principals: Simbulan-Rosenthal, Cynthia M., Rosenthal, Dean S., Luo, RuiBai, Li, Jia-He, Zhang, Jie, Smulson, Mark E.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2001
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC30380/
https://ncbi.nlm.nih.gov/pubmed/11160908
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