A Role for Serglycin Proteoglycan in Mast Cell Apoptosis Induced by a Secretory Granule-mediated Pathway

Mast cell secretory granules (secretory lysosomes) contain large amounts of fully active proteases bound to serglycin proteoglycan. Damage to the granule membrane will thus lead to the release of serglycin and serglycin-bound proteases into the cytosol, which potentially could lead to proteolytic ac...

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Bibliografiske detaljer
Main Authors: Melo, Fabio Rabelo, Waern, Ida, Rönnberg, Elin, Åbrink, Magnus, Lee, David M., Schlenner, Susan M., Feyerabend, Thorsten B., Rodewald, Hans-Reimer, Turk, Boris, Wernersson, Sara, Pejler, Gunnar
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Glycobiology and Extracellular Matrices
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3037655/
https://ncbi.nlm.nih.gov/pubmed/21123167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.176461
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