A Role for Serglycin Proteoglycan in Mast Cell Apoptosis Induced by a Secretory Granule-mediated Pathway

Mast cell secretory granules (secretory lysosomes) contain large amounts of fully active proteases bound to serglycin proteoglycan. Damage to the granule membrane will thus lead to the release of serglycin and serglycin-bound proteases into the cytosol, which potentially could lead to proteolytic ac...

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Hlavní autoři: Melo, Fabio Rabelo, Waern, Ida, Rönnberg, Elin, Åbrink, Magnus, Lee, David M., Schlenner, Susan M., Feyerabend, Thorsten B., Rodewald, Hans-Reimer, Turk, Boris, Wernersson, Sara, Pejler, Gunnar
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
Glycobiology and Extracellular Matrices
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3037655/
https://ncbi.nlm.nih.gov/pubmed/21123167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.176461
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