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The Lkb1 metabolic sensor maintains haematopoietic stem cell survival

Haematopoietic stem cells (HSCs) can convert between growth states that have marked differences in bioenergetic needs. Although often quiescent in adults, these cells become proliferative upon physiological demand. Balancing HSC energetics in response to nutrient availability and growth state is poo...

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Detaylı Bibliyografya
Asıl Yazarlar: Gurumurthy, Sushma, Xie, Stephanie Z., Alagesan, Brinda, Kim, Judith, Yusuf, Rushdia Z., Saez, Borja, Tzatsos, Alexandros, Ozsolak, Fatih, Milos, Patrice, Ferrari, Francesco, Park, Peter J., Shirihai, Orian S., Scadden, David T., Bardeesy, Nabeel
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3037591/
https://ncbi.nlm.nih.gov/pubmed/21124451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09572
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