The Lkb1 metabolic sensor maintains haematopoietic stem cell survival

Haematopoietic stem cells (HSCs) can convert between growth states that have marked differences in bioenergetic needs. Although often quiescent in adults, these cells become proliferative upon physiological demand. Balancing HSC energetics in response to nutrient availability and growth state is poo...

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Detalhes bibliográficos
Main Authors: Gurumurthy, Sushma, Xie, Stephanie Z., Alagesan, Brinda, Kim, Judith, Yusuf, Rushdia Z., Saez, Borja, Tzatsos, Alexandros, Ozsolak, Fatih, Milos, Patrice, Ferrari, Francesco, Park, Peter J., Shirihai, Orian S., Scadden, David T., Bardeesy, Nabeel
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3037591/
https://ncbi.nlm.nih.gov/pubmed/21124451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09572
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