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Nifedipine Inhibits Cardiac Hypertrophy and Left Ventricular Dysfunction in Response to Pressure Overload
Pathological hypertrophy is commonly induced by activation of protein kinases phosphorylating class II histone deacetylases (HDACs) and de-suppression of transcription factors, such as NFAT. We hypothesized that nifedipine, an L-type Ca(2+) channel blocker, inhibits Ca(2+) -calmodulin dependent kina...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3036765/ https://ncbi.nlm.nih.gov/pubmed/20559781 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12265-010-9182-x |
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