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TAK1 Lys-158 but not Lys-209 is required for IL-1β-induced Lys63-linked TAK1 polyubiquitination and IKK/NF-κB activation
The nuclear factor kappa B (NF-κB) transcription factors-mediated transcription is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli. Both the proteolytic and non-proteolytic functions of ubiquitination are critically important for the regulation of...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3035988/ https://ncbi.nlm.nih.gov/pubmed/21130870 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2010.11.017 |
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