Helicobacter pylori CagA activates NF-κB by targeting TAK1 for TRAF6-mediated Lys 63 ubiquitination

Helicobacter pylori-initiated chronic gastritis is characterized by the cag pathogenicity island-dependent upregulation of proinflammatory cytokines, which is largely mediated by the transcription factor nuclear factor (NF)-κB. However, the cag pathogenicity island-encoded proteins and cellular sign...

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Detalhes bibliográficos
Main Authors: Lamb, Acacia, Yang, Xiao-Dong, Tsang, Ying-Hung N, Li, Jiang-Dong, Higashi, Hideaki, Hatakeyama, Masanori, Peek, Richard M, Blanke, Steven R, Chen, Lin-Feng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Scientific Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775174/
https://ncbi.nlm.nih.gov/pubmed/19820695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2009.210
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