Загрузка...

Caveolin-1 negatively regulates a metalloprotease-dependent epidermal growth factor receptor transactivation by angiotensin II

A metalloprotease, ADAM17, mediates the generation of mature ligands for the epidermal growth factor receptor (EGFR). This is the key signaling step by which angiotensin II (AngII) induces EGFR transactivation leading to hypertrophy and migration of vascular smooth muscle cells (VSMCs). However, the...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Takaguri, Akira, Shirai, Heigoro, Kimura, Keita, Hinoki, Akinari, Eguchi, Kunie, Carlile-Klusacek, MaryEllen, Yang, Baohua, Rizzo, Victor, Eguchi, Satoru
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035769/
https://ncbi.nlm.nih.gov/pubmed/21172357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2010.12.009
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!