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Distinct Roles of Protease-Activated Receptors in Signal Transduction Regulation of Endothelial Nitric Oxide Synthase

Protease-activated receptors such as PAR1 and PAR2 have been implicated in the regulation of endothelial nitric oxide production. We hypothesized that PAR1 and PAR2 distinctly regulate the activity of endothelial nitric oxide synthase through the selective phosphorylation of a positive regulatory si...

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Detalhes bibliográficos
Main Authors: Suzuki, Hiroyuki, Motley, Evangeline D., Eguchi, Kunie, Hinoki, Akinari, Shirai, Heigoro, Watts, Vabren, Stemmle, Laura N., Fields, Timothy A., Eguchi, Satoru
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679177/
https://ncbi.nlm.nih.gov/pubmed/19064814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.108.125229
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