Central Role of G(q) in the Hypertrophic Signal Transduction of Angiotensin II in Vascular Smooth Muscle Cells

The angiotensin II (AngII) type 1 receptor (AT(1)) plays a critical role in hypertrophy of vascular smooth muscle cells (VSMCs). Although it is well known that G(q) is the major G protein activated by the AT(1) receptor, the requirement of G(q) for AngII-induced VSMC hypertrophy remains unclear. By...

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Main Authors: Ohtsu, Haruhiko, Higuchi, Sadaharu, Shirai, Heigoro, Eguchi, Kunie, Suzuki, Hiroyuki, Hinoki, Akinari, Brailoiu, Eugen, Eckhart, Andrea D., Frank, Gerald D., Eguchi, Satoru
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2453088/
https://ncbi.nlm.nih.gov/pubmed/18356277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2007-1694
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