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Quantifying Protein Function Specificity in the Gene Ontology

Quantitative or numerical metrics of protein function specificity made possible by the Gene Ontology are useful in that they enable development of distance or similarity measures between protein functions. Here we describe how to calculate four measures of function specificity for GO terms: 1) numbe...

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Detalhes bibliográficos
Main Authors: Louie, Brenton, Bergen, Silas, Higdon, Roger, Kolker, Eugene
Formato: Artigo
Idioma:Inglês
Publicado em: Michigan State University 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035283/
https://ncbi.nlm.nih.gov/pubmed/21304708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4056/sigs.561626
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