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The necessity of adjusting tests of protein category enrichment in discovery proteomics

Motivation: Enrichment tests are used in high-throughput experimentation to measure the association between gene or protein expression and membership in groups or pathways. The Fisher's exact test is commonly used. We specifically examined the associations produced by the Fisher test between pr...

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Detalhes bibliográficos
Main Authors: Louie, Brenton, Higdon, Roger, Kolker, Eugene
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995116/
https://ncbi.nlm.nih.gov/pubmed/21068002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq541
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