Common Fragile Site Tumor Suppressor Genes and Corresponding Mouse Models of Cancer

Chromosomal common fragile sites (CFSs) are specific mammalian genomic regions that show an increased frequency of gaps and breaks when cells are exposed to replication stress in vitro. CFSs are also consistently involved in chromosomal abnormalities in vivo related to cancer. Interestingly, several...

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Main Authors: Drusco, Alessandra, Pekarsky, Yuri, Costinean, Stefan, Antenucci, Anna, Conti, Laura, Volinia, Stefano, Aqeilan, Rami I., Huebner, Kay, Zanesi, Nicola
פורמט: Artigo
שפה:Inglês
יצא לאור: Hindawi Publishing Corporation 2011
נושאים:
Review Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035048/
https://ncbi.nlm.nih.gov/pubmed/21318118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/984505
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