Common Fragile Site Tumor Suppressor Genes and Corresponding Mouse Models of Cancer

Chromosomal common fragile sites (CFSs) are specific mammalian genomic regions that show an increased frequency of gaps and breaks when cells are exposed to replication stress in vitro. CFSs are also consistently involved in chromosomal abnormalities in vivo related to cancer. Interestingly, several...

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Main Authors: Drusco, Alessandra, Pekarsky, Yuri, Costinean, Stefan, Antenucci, Anna, Conti, Laura, Volinia, Stefano, Aqeilan, Rami I., Huebner, Kay, Zanesi, Nicola
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 2011
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Review Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035048/
https://ncbi.nlm.nih.gov/pubmed/21318118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/984505
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