Common Fragile Site Tumor Suppressor Genes and Corresponding Mouse Models of Cancer

Chromosomal common fragile sites (CFSs) are specific mammalian genomic regions that show an increased frequency of gaps and breaks when cells are exposed to replication stress in vitro. CFSs are also consistently involved in chromosomal abnormalities in vivo related to cancer. Interestingly, several...

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Hlavní autoři: Drusco, Alessandra, Pekarsky, Yuri, Costinean, Stefan, Antenucci, Anna, Conti, Laura, Volinia, Stefano, Aqeilan, Rami I., Huebner, Kay, Zanesi, Nicola
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2011
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Review Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035048/
https://ncbi.nlm.nih.gov/pubmed/21318118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/984505
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