Collagen binding specificity of the discoidin domain receptors: Binding sites on collagens II and III and molecular determinants for collagen IV recognition by DDR1

The discoidin domain receptors, DDR1 and DDR2 are cell surface receptor tyrosine kinases that are activated by triple-helical collagen. While normal DDR signalling regulates fundamental cellular processes, aberrant DDR signalling is associated with several human diseases. We previously identified GV...

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Hauptverfasser: Xu, Huifang, Raynal, Nicolas, Stathopoulos, Stavros, Myllyharju, Johanna, Farndale, Richard W., Leitinger, Birgit
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034869/
https://ncbi.nlm.nih.gov/pubmed/21044884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2010.10.004
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