Novel Properties of Tyrosine-mutant AAV2 Vectors in the Mouse Retina

Vectors based on adeno-associated virus serotype 2 (AAV2) have been used extensively in many gene-delivery applications, including several successful clinical trials for one type of Leber congenital amaurosis in the retina. Many studies have focused on improving AAV2 transduction efficiency and cell...

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Main Authors: Petrs-Silva, Hilda, Dinculescu, Astra, Li, Qiuhong, Deng, Wen-Tao, Pang, Ji-jing, Min, Seok-Hong, Chiodo, Vince, Neeley, Andy W, Govindasamy, Lakshmanan, Bennett, Antonette, Agbandje-McKenna, Mavis, Zhong, Li, Li, Baozheng, Jayandharan, Giridhara R, Srivastava, Arun, Lewin, Alfred S, Hauswirth, William W
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2011
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034844/
https://ncbi.nlm.nih.gov/pubmed/21045809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.234
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