High-efficiency Transduction of Human Monocyte-derived Dendritic Cells by Capsid-modified Recombinant AAV2 Vectors

Phosphorylation of surface-exposed tyrosine residues negatively impacts the transduction efficiency of recombinant AAV2 vectors. Pre-treatment of cells with specific cellular serine/threonine kinase inhibitors also significantly increased the transduction efficiency of AAV2 vectors. We reasoned that...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Aslanidi, George V., Rivers, Angela E., Ortiz, Luis, Govindasamy, Lakshmanan, Ling, Chen, Jayandharan, Giridhara R., Zolotukhin, Sergei, Agbandje-McKenna, Mavis, Srivastava, Arun
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356484/
https://ncbi.nlm.nih.gov/pubmed/22497875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2012.03.079
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky