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Effects of Varying Gene Targeting Parameters on Processing of Recombination Intermediates by ERCC1-XPF

The ERCC1-XPF structure-specific endonuclease is necessary for correct processing of homologous recombination intermediates requiring the removal of end-blocking nonhomologies. We previously showed that targeting the endogenous CHO APRT locus with plasmids designed to generate such intermediates rev...

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Bibliografische gegevens
Hoofdauteurs: Rahn, Jennifer J., Rowley, Brian, Lowery, Megan P., Coletta, Luis Della, Limanni, Tiffany, Nairn, Rodney S., Adair, Gerald M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034777/
https://ncbi.nlm.nih.gov/pubmed/21123118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2010.10.011
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