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Effects of Varying Gene Targeting Parameters on Processing of Recombination Intermediates by ERCC1-XPF
The ERCC1-XPF structure-specific endonuclease is necessary for correct processing of homologous recombination intermediates requiring the removal of end-blocking nonhomologies. We previously showed that targeting the endogenous CHO APRT locus with plasmids designed to generate such intermediates rev...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3034777/ https://ncbi.nlm.nih.gov/pubmed/21123118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2010.10.011 |
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