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Characterization of CHO XPF mutant UV41: Influence of XPF heterozygosity on double-strand break-induced intrachromosomal recombination
The UV hypersensitive CHO cell mutant UV41 is the archetypal XPF mammalian cell mutant, and was essential for cloning the human nucleotide excision repair (NER) gene XPF by DNA transfection and rescue. The ERCC1 and XPF genes encode proteins that form the heterodimer responsible for making incisions...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2574431/ https://ncbi.nlm.nih.gov/pubmed/18547876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2008.04.012 |
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