Smac mimetic-derived augmentation of chemotherapeutic response in experimental pancreatic cancer

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is highly resistant to conventional chemotherapy, in part due to the overexpression of inhibitors of apoptosis proteins (IAPs). Smac is an endogenous IAP-antagonist, which renders synthetic Smac mimetics attractive anticancer agents. We evaluated t...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Awasthi, Niranjan, Kirane, Amanda, Schwarz, Margaret A, Toombs, Jason E, Brekken, Rolf A, Schwarz, Roderich E
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034706/
https://ncbi.nlm.nih.gov/pubmed/21226944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-15
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars