Clinicopathologic Correlations in a Large Alzheimer Disease Center Autopsy Cohort: Neuritic Plaques and Neurofibrillary Tangles “Do Count” When Staging Disease Severity

There is uncertainty regarding the association of cognitive decline in Alzheimer disease (AD) with classic histopathologic features—neurofibrillary tangles (NFTs) and “neuritic” amyloid plaques (NPs). This uncertainty fuels doubts about the diagnostic importance of NFTs and NPs and leads to confusio...

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Detalhes bibliográficos
Main Authors: Nelson, Peter T., Jicha, Gregory A., Schmitt, Frederick A., Liu, Huaichen, Davis, Daron G., Mendiondo, Marta S., Abner, Erin L., Markesbery, William R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034246/
https://ncbi.nlm.nih.gov/pubmed/18090922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/nen.0b013e31815c5efb
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