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Hyperspectral Raman imaging of neuritic plaques and neurofibrillary tangles in brain tissue from Alzheimer’s disease patients

Neuritic plaques and neurofibrillary tangles are crucial morphological criteria for the definite diagnosis of Alzheimer’s disease. We evaluated 12 unstained frontal cortex and hippocampus samples from 3 brain donors with Alzheimer’s disease and 1 control with hyperspectral Raman microscopy on sample...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Michael, Ralph, Lenferink, Aufried, Vrensen, Gijs F. J. M., Gelpi, Ellen, Barraquer, Rafael I., Otto, Cees
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5688091/
https://ncbi.nlm.nih.gov/pubmed/29142266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16002-3
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