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Simvastatin reverses cardiac hypertrophy caused by disruption of the bradykinin 2 receptor
Bradykinin 2 receptor (B2R) deficiency predisposes to cardiac hypertrophy and hypertension. The pathways mediating these effects are not known. Two-month-old B2R knockout (KO) and wild-type (WT) mice were assigned to 4 treatment groups (n = 12–14/group): control (vehicle); nitro-l-arginine methyl es...
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| Glavni autori: | , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3034156/ https://ncbi.nlm.nih.gov/pubmed/18758513 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1139/y08-068 |
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