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Simvastatin inhibits noradrenaline-induced hypertrophy of cultured neonatal rat cardiomyocytes

1. Oxidative mechanisms have been implicated in neonatal cardiomyocyte hypertrophy. We and others have shown that a HMG-CoA reductase inhibitor preserves endogenous antioxidant enzyme activity and inhibits cardiac hypertrophy in vivo. We therefore have examined whether noradrenaline (NA) induces the...

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Bibliografske podrobnosti
Main Authors: Luo, Jian-Dong, Xie, Fang, Zhang, Wei-Wen, Ma, Xiao-Dong, Guan, Jin-Xia, Chen, Xiu
Format: Artigo
Jezik:Inglês
Izdano: 2001
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572550/
https://ncbi.nlm.nih.gov/pubmed/11156573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703792
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