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Simvastatin inhibits noradrenaline-induced hypertrophy of cultured neonatal rat cardiomyocytes
1. Oxidative mechanisms have been implicated in neonatal cardiomyocyte hypertrophy. We and others have shown that a HMG-CoA reductase inhibitor preserves endogenous antioxidant enzyme activity and inhibits cardiac hypertrophy in vivo. We therefore have examined whether noradrenaline (NA) induces the...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572550/ https://ncbi.nlm.nih.gov/pubmed/11156573 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703792 |
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