Učitavanje...
Carbonic anhydrase inhibition prevents and reverts cardiomyocyte hypertrophy
Hypertrophic cardiomyocyte growth contributes substantially to the progression of heart failure. Activation of the plasma membrane Na(+)–H(+) exchanger (NHE1) and Cl(−)–HCO(3)(−) exchanger (AE3) has emerged as a central point in the hypertrophic cascade. Both NHE1 and AE3 bind carbonic anhydrase (CA...
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| Glavni autori: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Blackwell Science Inc
2007
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2075384/ https://ncbi.nlm.nih.gov/pubmed/17124262 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.123638 |
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