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Disruption of coordinated cardiac hypertrophy and angiogenesis contributes to the transition to heart failure
Although increased external load initially induces cardiac hypertrophy with preserved contractility, sustained overload eventually leads to heart failure through poorly understood mechanisms. Here we describe a conditional transgenic system in mice characterized by the sequential development of adap...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1180541/ https://ncbi.nlm.nih.gov/pubmed/16075055 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI24682 |
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