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Short-Term Akt Activation in Cardiac Muscle Cells Improves Contractile Function in Failing Hearts
Akt is a serine/threonine protein kinase that is activated by a variety of growth factors or cytokines in a phosphatidylinositol 3-kinase–dependent manner. By using a conditional transgenic system in which Akt signaling can be turned on or off in the adult heart, we previously showed that short-term...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Investigative Pathology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3509766/ https://ncbi.nlm.nih.gov/pubmed/23031259 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.08.020 |
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