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Microglia Mediate the Clearance of Soluble Aβ through Fluid Phase Macropinocytosis

Alzheimer's disease is characterized by the progressive deposition of β-amyloid (Aβ) within the brain parenchyma and its subsequent accumulation into senile plaques. Pathogenesis of the disease is associated with perturbations in Aβ homeostasis and the inefficient clearance of these soluble and...

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Detalles Bibliográficos
Main Authors: Mandrekar, Shweta, Jiang, Qingguang, Lee, C. Y. Daniel, Koenigsknecht-Talboo, Jessica, Holtzman, David M., Landreth, Gary E.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034143/
https://ncbi.nlm.nih.gov/pubmed/19339619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5572-08.2009
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