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PPARγ agonists as therapeutics for the treatment of Alzheimer’s disease

Alzheimer’s disease (AD) is characterized by the deposition of β-amyloid within the brain parenchyma and is accompanied by the impairment of neuronal metabolism and function, leading to extensive neuronal loss. The disease involves the perturbation of synaptic function, energy, and lipid metabolism....

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Detalhes bibliográficos
Main Authors: Landreth, Gary, Jiang, Qingguang, Mandrekar, Shweta, Heneka, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593876/
https://ncbi.nlm.nih.gov/pubmed/18625459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nurt.2008.05.003
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