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Microglia Mediate the Clearance of Soluble Aβ through Fluid Phase Macropinocytosis

Alzheimer's disease is characterized by the progressive deposition of β-amyloid (Aβ) within the brain parenchyma and its subsequent accumulation into senile plaques. Pathogenesis of the disease is associated with perturbations in Aβ homeostasis and the inefficient clearance of these soluble and...

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Autori principali: Mandrekar, Shweta, Jiang, Qingguang, Lee, C. Y. Daniel, Koenigsknecht-Talboo, Jessica, Holtzman, David M., Landreth, Gary E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034143/
https://ncbi.nlm.nih.gov/pubmed/19339619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5572-08.2009
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