Development and validation of a high-performance liquid chromatography/tandem mass spectrometry method for the determination of artemether and its active metabolite dihydroartemisinin in human plasma

To study the pharmacokinetic profile of artemether in children and in the context of antiviral drugs for HIV infected patients co-infected with malaria, an LC-MS/MS method was developed and validated to simultaneously determine artemether and its metabolite dihydroartemisinin in human plasma. Using...

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Bibliografiske detaljer
Main Authors: Huang, Liusheng, Jayewardene, Anura L., Li, Xiaohua, Marzan, Florence, Lizak, Patricia S., Aweeka, Francesca T.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034030/
https://ncbi.nlm.nih.gov/pubmed/19646837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpba.2009.06.051
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