Asf1b, the necessary Asf1 isoform for proliferation, is predictive of outcome in breast cancer

Mammalian cells possess two isoforms of the histone H3–H4 chaperone anti-silencing function 1 (Asf1), Asf1a and Asf1b. However to date, whether they have individual physiological roles has remained elusive. Here, we aim to elucidate the functional importance of Asf1 isoforms concerning both basic an...

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Autors principals: Corpet, Armelle, De Koning, Leanne, Toedling, Joern, Savignoni, Alexia, Berger, Frédérique, Lemaître, Charlène, O'Sullivan, Roderick J, Karlseder, Jan, Barillot, Emmanuel, Asselain, Bernard, Sastre-Garau, Xavier, Almouzni, Geneviève
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034011/
https://ncbi.nlm.nih.gov/pubmed/21179005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.335
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