Structural insight into how the human helicase subunit MCM2 may act as a histone chaperone together with ASF1 at the replication fork

MCM2 is a subunit of the replicative helicase machinery shown to interact with histones H3 and H4 during the replication process through its N-terminal domain. During replication, this interaction has been proposed to assist disassembly and assembly of nucleosomes on DNA. However, how this interacti...

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Foilsithe in:Nucleic Acids Res
Main Authors: Richet, Nicolas, Liu, Danni, Legrand, Pierre, Velours, Christophe, Corpet, Armelle, Gaubert, Albane, Bakail, May, Moal-Raisin, Gwenaelle, Guerois, Raphael, Compper, Christel, Besle, Arthur, Guichard, Berengère, Almouzni, Genevieve, Ochsenbein, Françoise
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2015
Ábhair:
Structural Biology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4330383/
https://ncbi.nlm.nih.gov/pubmed/25618846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv021
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